- # Gastrointestinal & Acid Reflux Relief: US Cash Price Guide 2026
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- Proton pump inhibitors (PPIs) and H2-receptor antagonists are essential daily therapies for tens of millions suffering from GERD, peptic ulcer disease, and erosive esophagitis.
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- ## Top Monitored Gastrointestinal Medications
- - **Omeprazole (Prilosec)**: Standard 20mg and 40mg delayed-release capsules. Cash prices range from $12 to $60 depending on retail venue.
- - **Pantoprazole Sodium (Protonix)**: Highly effective delayed-release PPI commonly prescribed post-hospitalization.
- - **Esomeprazole (Nexium)**: S-enantiomer PPI providing sustained gastric acid suppression.
- - **Famotidine (Pepcid)**: Rapid-acting H2 blocker suitable for intermittent acid relief and histamine reduction.
- - **Sucralfate (Carafate)**: Mucosal protective barrier medication for active duodenal ulcers.
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- ### Price Comparison & Online Fulfillment
- Compare prices across verified national pharmacies and digital discount cards at [RxMatch US](https://us-pharmacy.vercel.app).
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- - [Omeprazole Price Comparison](https://us-pharmacy.vercel.app/drugs/omeprazole)
- - [Complete 100+ FDA Drug Directory](https://us-pharmacy.vercel.app/drugs)
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- For international mail order fulfillment with discrete home delivery, visit [PharmStore](http://pharm-store.com/?id=924) and apply promo code **pu-8992** for 5% off.