# Gastrointestinal & Acid Reflux Relief: US Cash Price Guide 2026 Proton pump inhibitors (PPIs) and H2-receptor antagonists are essential daily therapies for tens of millions suffering from GERD, peptic ulcer disease, and erosive esophagitis. ## Top Monitored Gastrointestinal Medications - **Omeprazole (Prilosec)**: Standard 20mg and 40mg delayed-release capsules. Cash prices range from $12 to $60 depending on retail venue. - **Pantoprazole Sodium (Protonix)**: Highly effective delayed-release PPI commonly prescribed post-hospitalization. - **Esomeprazole (Nexium)**: S-enantiomer PPI providing sustained gastric acid suppression. - **Famotidine (Pepcid)**: Rapid-acting H2 blocker suitable for intermittent acid relief and histamine reduction. - **Sucralfate (Carafate)**: Mucosal protective barrier medication for active duodenal ulcers. ### Price Comparison & Online Fulfillment Compare prices across verified national pharmacies and digital discount cards at [RxMatch US](https://us-pharmacy.vercel.app). - [Omeprazole Price Comparison](https://us-pharmacy.vercel.app/drugs/omeprazole) - [Complete 100+ FDA Drug Directory](https://us-pharmacy.vercel.app/drugs) For international mail order fulfillment with discrete home delivery, visit [PharmStore](http://pharm-store.com/?id=924) and apply promo code **pu-8992** for 5% off.